منابع مشابه
Tumor Burden Talks in Cancer Treatment with PEGylated Liposomal Drugs
PURPOSE PEGylated liposomes are important drug carriers that can passively target tumor by enhanced permeability and retention (EPR) effect in neoplasm lesions. This study demonstrated that tumor burden determines the tumor uptake, and also the tumor response, in cancer treatment with PEGylated liposomal drugs in a C26/tk-luc colon carcinoma-bearing mouse model. METHODS Empty PEGylated liposo...
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Thyroid cancer is an important malignancy with relatively high incidence among women in middle east (Larijani et al., 2005; Larijani et al., 2004; Mohagheghi et al., 2009) and many part of the world (Salim et al., 2010) like Iran (Sanii et al., 2012; Haghpanah et al., 2006). The incidence has been increasing with rate of up to 3% in countries that reliable cancer registry exits (Morris et al., ...
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BACKGROUND Increased number of single nucleotide substitutions is seen in breast and ovarian cancer genomes carrying disease-associated mutations in BRCA1 or BRCA2. The significance of these genome-wide mutations is unknown. We hypothesize genome-wide mutation burden mirrors deficiencies in DNA repair and is associated with treatment outcome in ovarian cancer. METHODS AND RESULTS The total nu...
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Objective(s): In the developed countries, one of the leading causes of death is cancer. Cancer cells with their unique and destructive characteristics impose high costs on communities. Methods: In this study, we will review the latest cancer researches an...
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ژورنال
عنوان ژورنال: JAMA Oncology
سال: 2021
ISSN: 2374-2437
DOI: 10.1001/jamaoncol.2020.6371